Novel Missense Variant Analysis

  • The Effects of any theoretical missense variants can be predicted here.
  • Codons are numbered with respect to the HGVS nomenclature-with codon 1 representing the first residue (Met) of the signal peptide.
  • You may select any one option for the "Variant Amino Acid".


Multiple Sequence Alignment of Factor VII protein sequence across Primates    

Note: Dragging the mouse will take you across the sequence limits
Note: AA numbering is for human FVII and is HGVS

FVII HUMAN P08709  |  FVII CHIMPANZEE H2Q7T8 |  FVII GORILLA G3RDW8 |  FVII GIBBON G1QI28
FVII BUSHBABY B5SNI1 |  FVII MARMOSET F7FP08