Novel Missense Variant Analysis


  • The Effects of any theoretical missense mutations can be predicted here.
  • Codons are numbered with respect to the HGVS nomenclature-with codon 1 representing the first residue (Met) of the signal peptide.
  • You may select any one option for the "Variant Amino Acid".


Multiple Sequence Alignment of Factor VII protein sequence across Primates.    

Note: Clicking and Dragging will take you across the sequence limits
Note: All numbering is for human FVII and is HGVS

FVII_HUMAN_P08709 | FVII_CHIMPANZEE_H2Q7T8| FVII_GORILLA_G3RDW8| FVII_GIBBON_G1QI28| FVII_BUSHBABY_B5SNI1| FVII_MARMOSET_F7FP08