Point Mutations Mapped on to the FVII amino acid sequence



image/svg+xml 1 466 Gla 61 105 EGF1 106 142 EGF2 147 188 Serine Protease 213 452 21 60 194 212

KEY = DOMAINS:: Sigpeptide-- Propeptide-- Gla -- EGF1 -- Linker-- EGF2 -- Actpeptide--   SP  

MVSQALRLLC   LLLGLQGCLA   AGGVAKASGG   ETRDMPWKPG   PHRVFVTQEE      50

AHGVLHRRRR   ANAFLEELRP   GSLERECKEE   QCSFEEAREI   FKDAERTKLF      100

WISYSDGDQC   ASSPCQNGGS   CKDQLQSYIC   FCLPAFEGRN   CETHKDDQLI      150

CVNENGGCEQ   YCSDHTGTKR   SCRCHEGYSL   LADGVSCTPT   VEYPCGKIPI      200

LEKRNASKPQ   GRIVGGKVCP   KGECPWQVLL   LVNGAQLCGG   TLINTIWVVS      250

AAHCFDKIKN   WRNLIAVLGE   HDLSEHDGDE   QSRRVAQVII   PSTYVPGTTN      300

HDIALLRLHQ   PVVLTDHVVP   LCLPERTFSE   RTLAFVRFSL   VSGWGQLLDR      350

GATALELMVL   NVPRLMTQDC   LQQSRKVGDS   PNITEYMFCA   GYSDGSKDSC      400

KGDSGGPHAT   HYRGTWYLTG   IVSWGQGCAT   VGHFGVYTRV   SQYIEWLQKL      450

MRSEPRPGVL   LRAPFP